Ulcerative Colitis

Ulcerative Colitis

It is a chronic inflammatory disease of the large intestine.

The disease occurs when the immune system sees the submucosa, which is just below the mucosal layer of the intestinal surface, as foreign matter and destroy it.

In this case, the mucosa cells can not be feed, wide ulcers and inflammatory reaction occur in the large intestine. There may be bleeding in the stool. It has common abdominal pain and diarrhea 20-25 times a day. Diagnose is by colonoscopy.

Commonly applied treatments are drugs such as salozopyrine and salofoquin which suppress inflammatory reaction. In worse patients, cortisone and cancer drugs such as immurane or methotrexate, which prevent the immune system functioning, are used.

However, these treatments can not provide a permanent improvement since the cause of disease has not been removed. The main problem is not in the immune system, but in the submucosa of the large intestine. Immune complex molecules accumulating in the submucosa mark it as an incorrect target.

An ideal treatment method;

The immune complex accumulation in the submucosa should be lifted, preventing reconstruction.

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